Septin 2 anticorps (AA 275-325)

N° du produit ABIN7450720

Cet anticorps Lapin Polyclonal détecte spécifiquement Septin 2 dans WB et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Septin 2 anticorps (AA 275-325) (ABIN7450720)

Antigène: Septin 2 (SEPT2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Septin 2 anticorps

Épitope: AA 275-325

Fonction: Rabbit anti-Septin 2 Antibody, Affinity Purified

Homologie: Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 275 and 325

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: Septin 2

Sujet: Background: Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements [taken from the Universal Protein Resource (UniProt) Q15019].

ID gène: 4735

NCBI Accession: NP_001008491

UniProt: Q15019